Pdf new approach in the treatment of subacute thyroiditis. Pdf subacute thyroiditis develops as a result of viral infections andor postviral inflammatory responses. A selflimiting, virally induced inflammation of the thyroid characterised by a febrile illness and swelling of the thyroid, with subsequent damage to the thyroid tissue causing leakage of thyroid hormones into the circulation. Subacute thyroiditis occurs most often in middleaged women with symptoms of a viral upper respiratory tract infection in the past month. Sometimes, the pain can spread radiate to the jaw or ears. Subacute thyroiditis subacute thyroiditis follows the same clinical course as painless and postpartum thyroiditis, but is often accompanied by thyroidal pain. The thyroidal pain in patients with subacute thyroiditis usually follows the same timeframe of the thyrotoxic phase months. Subacute thyroiditis an overview sciencedirect topics. Subacute thyroiditis sat, or granulomatous thyroiditis, is an inflammatory thyroid condition associated. Nov 11, 2019 subacute thyroiditis subacute granulomatous thyroiditis is characterized by neck pain or discomfort, a tender diffuse goiter, and a predictable course of thyroid function evolution. An evaluation of the results of the steroid and non. The syndrome is not commonly recognized in this age. Apr 12, 2015 subacute thyroiditis sat is an inflammatory condition of the thyroid with characteristic presentations and clinical course.
At times, the pain begins and may be confined to the one lobe, but usually spreads. Subacute granulomatous thyroiditis is an uncommon disease that occurs most often in women in their second to fifth decades of life. Mumps virus, influenza virus, and other respiratory viruses have been found to cause subacute thyroiditis. Subacute thyroiditis sometimes presents as a solitary cold nodule. The condition often occurs after a viral infection of the upper respiratory tract. Initial hyperthyroidism is common, sometimes followed by a transient period of hypothyroidism. Chinese herbal medicine for subacute thyroiditis core. Subacute thyroiditis msd manual professional edition. Inflammatory or destructive changes in the thyroid gland are thought to be involved in the production of the tshreceptor antibodies in the patient.
We herein present the ct and mr imaging findings of two cases of. They include conditions that cause acute illness with severe thyroid pain eg, subacute thyroiditis and infectious thyroiditis and conditions in which there is no clinically evident inflammation and the illness is manifested primarily by thyroid dysfunction or. Hashimotos thyroiditis associated to subacute thyroiditis. Thyroiditis can also be seen in patients taking the drugs interferon and amiodarone.
Subacute symptoms last longer than acute symptoms, but are not chronic. Subacute thyroiditis is generally felt to have a viral etiology, and the diagnosis is usually. The disease resolves spontaneously, usually without thyroid function abnormalities. Subacute thyroiditis subacute granulomatous thyroiditis is characterized by neck pain or discomfort, a tender diffuse goiter, and a predictable course of thyroid function evolution. This disease usually presents with thyroid tenderness, a low grade fever, and occasional dysphagia. The thyroid gland is located in the neck, just above where your collarbones meet in the middle. Granulomatous thyroiditis, pfsat typically present with painful swelling of the thyroid. Nov 15, 2019 subacute thyroiditis sat is an inflammatory thyroid disease.
Subacute thyroiditis is the major cause of pain in the thyroid. An evaluation of the results of the steroid and nonsteroidal. Extremely dangerous is the situation when the diagnosis of sat is erroneously made based on criteria other than ultrasound us. Diagnosis is clinical and with thyroid function tests. Thyroid primary and metastatic malignant tumours of poor. Subacute thyroiditis endocrine and metabolic disorders. Subacute thyroiditis is a disease in which fever and thyroid pain accompanies inflammation of the thyroid gland. The main purpose of the treatment is to relieve pain and control the inflammatory process. Clinical features and outcome of subacute thyroiditis in an. People with this condition will also have symptoms of hyperthyroidism and later develop symptoms. May 30, 2016 recurring seasonal subacute thyroiditis. Hyperthyroidism with painless subacute thyroiditis in the. Thyroid is exquisitely tender, hard, mild to moderately. Subacute thyroiditis knowledge for medical students and.
Serum thyrotrophin response to thyrotrophin releasing hormone and the concentration of free thyroxine in subacute thyroiditis. Pdf hashimotos thyroiditis associated to subacute thyroiditis. I was severely hyper for 5 months, then went hypo for about 3 months, then had what felt like a total recurrence may thru july of 2015. While subacute granulomatous thyroiditis usually occurs after a viral upper respiratory tract infection. Subacute thyroiditis is a selflimiting disorder with most of the patients making a complete recovery. Localized subacute thyroiditis presenting as a painful hot. Pdf download jerry, a 48yearold white man, is referred to endocrinology for abnormal results of thyroid tests performed four weeks ago see table for values.
Subacute thyroiditis is an acute inflammatory disease of the thyroid probably caused by a virus. Subacute thyroiditis refers to a transient patchy inflammation of the thyroid gland that is associated either with granuloma formation subacute granulomatous thyroiditis or lymphocytic infiltration subacute lymphocytic thyroiditis. Thyroiditis definition of thyroiditis by the free dictionary. Proceeding according to these diagnostic criteria may lead to an incorrect diagnosis and treatment. Localized subacute thyroiditis presenting as a painful hot nodule. The term thyroiditis encompasses a diverse group of disorders characterized by some form of thyroid inflammation. Ct and mr imaging findings associated with subacute thyroiditis. Wed like to understand how you use our websites in order to improve them. Subacute thyroiditis is an uncommon condition thought to be caused by viral infection of the thyroid gland. Subacute thyroiditis may be responsible for 1520% of patients presenting with thyrotoxicosis and 10% of patients presenting with hypothyroidism.
Fever, dysphagia, malaise, fatigue, anxiety, sweats may occur. Here, the case of a 57yearold woman complaining of pain in the left neck and fatigue for. Painful subacute thyroiditis, which is a selflimited inflammatory disorder, is the most common cause of thyroid pain. Subacute thyroiditis painful subacute thyroiditis, 5% of clinical thyroid disease, often follows a viral upper respiratory illness mumps, coxsackie, influenza and adenovirus.
Painful subacute thyroiditis recurs in about 2 percent of individuals. It occurs in up to 5 percent of patients with clinical thyroid disease. Subacute thyroiditis is generally caused by viral infection and is the most common cause of a painful thyroid 1,3. Subacute thyroiditis sat is an inflammatory condition of the thyroid with characteristic presentations and clinical course. Clinical features and outcome of subacute thyroiditis. With subacute thyroiditis, there is generally a predictable pattern of how the thyroid functions. Lymphocytic thyroiditis with spontaneously resolving. It is thought to be the result of a viral infection. Subacute thyroiditis sat is an inflammatory thyroid disease. A diagnosis of subacute thyroiditis is readily considered when patients present with a particular set of typical clinical characteristics. Oct 08, 2018 subacute thyroiditis is a selflimited thyroid condition associated with a triphasic clinical course of hyperthyroidism, hypothyroidism, and return to normal thyroid function.
Ppt thyroiditis powerpoint presentation free to download. Subacute thyroiditis is an immune reaction of the thyroid gland that often follows an upper respiratory infection. Subacute thyroiditis definition of subacute thyroiditis by. Two months ago, jerry developed an upper respiratory infection uri with fever, odynophagia, and anterior neck discomfort. Subacute thyroiditis is a rare type of thyroiditis that causes pain and discomfort in the thyroid. The diagnosis of subacute thyroiditis sat is based mainly on the presence of painful thyroid goitre and a significant increase in erythrocyte sedimentation rate esr. The most obvious symptom of subacute thyroiditis is pain in the neck caused by a swollen and inflamed thyroid gland. Pdf clinical features and outcome of subacute thyroiditis in an.
Hello, in oct 2014 i was hospitalized for severe subacute thyroiditis. It is uncommon and can affect individuals of both sexes, occurring three times as often in women than in men. The incidence of subacute thyroiditis is approximately 12 times higher in women than in men, and it commonly occurs in females in their 30s and 40s. Downloaded from the american family physician web site at. It frequently follows an upper respiratory tract infection, and its incidence is highest in. Thyroiditis subacute thyroiditis subacute thyroiditis follows the same clinical course as painless and postpartum thyroiditis, but is often accompanied by thyroidal pain. Silent thyroiditis, also called subacute lymphocytic thyroiditis, classically presents with the same triphasic course described earlier for subacute thyroiditis. Hyperthyroidism is typically the presentation followed by euthyroidism, hypothyroidism, and ultimately restoration of normal thyroid function figure 1. Prodrome the precursor uri is followed in days or weeks by the clinical manifestations of sat.